Chemical Reactions of Omeprazole and Omeprazole Analogues. IV. Reactions of Compounds of the Omeprazole System with 2-Mercaptoethanol.

Abstract
When omeprazole, 5-methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridinylmethylsulfinyl)-1H-benzimidazole, is dissolved in dilute HCl various reaction products are obtained. The addition of 2-mercaptoethanol greatly simplifies the complexity of these reactions. The reactions between 2-mercaptoethanol and some of the degradation products have been studied in detail.