SINCE 1938 we have been seeking an operative procedure for the treatment of duodenal ulcer, one which would meet most of the desired criteria of surgical intervention and would result in the least postoperative disturbances to gastrointestinal functions. In 1954, we began a pilot study consecutively in 20 patients upon whom we performed distal antrectomies (25% or less gastrectomy) with bilateral vagectomies, Billroth II, anterior gastrojejunostomies, Hofmeister, or Polya types. The results in this group exceeded those obtained with other operations we had performed for chronic duodenal ulcer, so that in 1957 we began to perform the procedure to the exclusion of all others. To date we have performed 570 operations of this type. Purpose of Report. —Since the ultimate success of a surgical procedure for duodenal ulcer is measured in time, and apparently a five-year period holds some medical historic purpose, it is our plan to present our follow-up