The J Substance of Cattle

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Abstract
Summary: Studies of the titers of naturally occurring anti-J sera in two groups of cows, one consisting of 8 and the other of 23 animals, have shown that the concentration of anti-J varies considerably among individuals and for the same individual from one time to another. The rise and fall of anti-J levels among the first group of individuals studied during a 28-month period and among the second group studied during a 19-month period was correlated with the season of the year. In both groups of animals, the highest titers were found during the late summer and early autumn (August to October), and the lowest titers were found during the late autumn and winter (December to March). The physiologic basis for this striking seasonal variation is unknown at present.

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