MRI in Optic Neuritis-Reply

Publisher Website
Google Scholar
Abstract
In Reply. —My editorial on the Optic Neuritis Treatment Trial (ONTT) summarized the study design, but in such a format, many of the details of study procedures and subgroup analyses could not be discussed. Dr Blackwell cites the study by Miller et al that suggested that in cases of acute optic neuritis, MRI localization of the involved portion of the optic nerve and the extent of involvement may have prognostic value. My colleagues and I are certainly aware of this study and share Dr Blackwell's opinion about its potential significance. Miller et al used a fat-suppression scanning technique to identify lesions in the optic nerve. There is recent evidence that gadolinium-enhanced MRI can identify acute demyelination in the brain in patients with multiple sclerosis.1,2We have found that with this technique, optic nerve lesions can be identified in acute optic neuritis (Figure). At the present time, we are investigating

This publication has 0 references indexed in Scilit: