Unusual Ph1 Translocation in Acute Myeloblastic Leukemia
- 17 August 1978
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 299 (7) , 360
- https://doi.org/10.1056/nejm197808172990712
Abstract
To the Editor: A small number of Ph1+ acute myeloblastic leukemias and an even smaller number of acute lymphoblastic leukemias have been described.1 The Ph1 in these cases is indistinguishable from that occurring in chronic myelocytic leukemia, in which, as a rule, the 22q-deleted material is translocated upon the long arm of chromosome No. 9.2 In about 8 per cent of the cases of chronic myelocytic leukemia, however, the translocation is found on a chromosome other than No. 9.3 On the other hand, only cases of acute lymphoblastic and three of acute myeloblastic leukemia (one an erythroleukemia) have been . . .Keywords
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