Mitogenic activity of Mycoplasma pulmonis II. Studies on the biochemical nature of the mitogenic factor
- 1 February 1979
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 9 (2) , 149-154
- https://doi.org/10.1002/eji.1830090211
Abstract
The mitogenic activity of Mycoplasma pulmonis has been demonstrated to reside in the membrane of this microorganism. Studies aimed at the identification of the membraneous mitogenic factor have revealed that membrane proteins are essential components of this mitogenic manifestation. In addition, it has been shown that the microorganism's outer surface membrane proteins are responsible for mitogenic activity. It has been shown, however, that isolated membrane lipids are not mitogenic for rat lymphocytes and are not required for the membrane's mitogenic potential.This publication has 22 references indexed in Scilit:
- Activation of Human Lymphocyte Subpopulations by Mycoplasma pneumoniaeScandinavian Journal of Immunology, 1977
- Surface parasitism by Mycoplasma pneumoniae of respiratory epithelium.The Journal of Experimental Medicine, 1977
- Mycoplasma pneumoniae is a polyclonal B-cell activatorNature, 1976
- The outer membrane of Proteus mirabilis I. Isolation and characterization of the outer and cytoplasmic membrane fractionsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1975
- The outer membrane of Proteus mirabilis II. The extractable lipid fraction and electron-paramagnetic resonance analysis of the outer and cytoplasmic membranesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1975
- Characterization of the mycoplasma membrane proteins IV. Disposition of proteins in the membraneBiochimica et Biophysica Acta (BBA) - Biomembranes, 1974
- Cholesterol in mycoplasm membranes. Correlation of enzymic and transport activities with physical state of lipids in membranes of Mycoplasma mycoides var. capri adapted to grow with low cholesterol concentrationsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1973
- Cavitation as a Mechanism for the Synthesis of Natural DiamondsNature, 1973
- Selective reaggregation of solubilized mycoplasma-membrane proteins and the kinetics of membrane reformationBiochimica et Biophysica Acta (BBA) - Biomembranes, 1969
- Association of protein and lipid in Mycoplasma laidlawii membranes disaggregated by detergentsArchives of Biochemistry and Biophysics, 1967