Lignans of western red cedar (Thujaplicata Donn). X. γ-Thujaplicatene

Abstract
The structure of the tenth in the series of novel lignans from the heartwood of western red cedar (Thujaplicata Donn) has been determined as 2-(3″,4″-dihydroxy-5″-methoxybenzylidene)-3-(4′-hydroxy-3′-methoxybenzyl)-butyrolactone (γ-thujaplicatene) (1) by spectrometric methods and comparison with synthetic derivative reactions. The discovery of this lignan with a double bond conjugated with an aromatic ring confirms previously suggested biosynthetic routes to the cedar lignans.

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