Chiral Oxazaborolidinone-Mediated Enantioselective Ring-Cleavage Reaction of a Mixture of Diastereomeric 1,3-Dioxolane Acetals: Application to Asymmetric Desymmetrization of meso-1,2-Diols
- 2 January 2001
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 2001 (01) , 0061-0064
- https://doi.org/10.1055/s-2001-9730
Abstract
Ring-cleavage reaction of a mixture of diastereomeric dioxolane acetals syn- and anti-1b-e proceeds in an enantiodifferentiating manner in the presence of chiral Lewis acid 2. The reaction is utilized as a key step in asymmetric desymmetrization of meso-1,2-diols.Keywords
This publication has 0 references indexed in Scilit: