SEX HORMONE CHANGES IN MALE EPILEPTICS

Abstract
Mean plasma levels of LH, FSH, PRL, and sex‐hormone binding globulin (SHBG) were raised in twenty‐seven epileptics on anticonvulsants compared with age matched controls. Sexual activity appeared to be reduced. Anticonvul‐ sant therapy results in raised SHBG levels which may be associated with a lowered free testosterone level as indicated by raised LH levels and lowered sexual activity.

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