Chromosomal damage in chronic alcohol users

1 January 1975

journal article
research article
Published by Springer Nature in Human Genetics

Vol. 29 (3) , 191-200
https://doi.org/10.1007/bf00297623

Abstract

First in vitro mitoses were analysed from the peripheral leukocytes of 22 chronic alcohol users and of 18 controls. The frequency of exchange aberrations of the chromatid and chromosome type were significantly higher in the alcohol as compared with the control group. The results indicate an indirect or direct mutagenic activity of alcohol in vivo. Erste in vitro-Mitosen peripherer Leukocyten von 22 Alkoholikern und 18 Kontrollen wurden untersucht. Die Häufigkeiten von Austauschaberrationen vom Chromatiden und Chromosomentyp sind bei den Alkoholikern signifikant höher als bei den Kontrollen. Die Ergebnisse weisen auf eine indirekte oder direkte mutagene Wirkung von Alkohol in vivo hin.

Keywords

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