COMPARISON OF THIOREDOXIN REDUCTASES FROM NOVIKOFF ASCITES HEPATOMA-CELLS AND NORMAL LIVER OF RATS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 38  (7) , 1885-1888
Abstract
Adult rat liver contained variant forms of thioredoxin reductase [EC 1.6.4.5] with isoelectric points at pH 4.9 and at approximately pH 4.7 compared to pH 5.1 for the enzyme from Novikoff ascites hepatoma. Fetal and regenerating liver contained only the form with the isoelectric point at pH 4.9. All 3 enzymes precipitated with and were inhibited by a rabbit antibody to purified enzyme from Novikoff tumor.

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