Brain Donation
- 5 January 1989
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 320 (1) , 62-63
- https://doi.org/10.1056/nejm198901053200118
Abstract
To the Editor: Advances, particularly in molecular biology, have provided valuable new insights into the pathogenesis of human neuropsychiatric diseases.1 2 3 4 Numerous sophisticated techniques, such as the identification of mRNA, were initially carried out on tissues obtained from laboratory animals. Recently, human post-mortem tissues have also been found to be useful in such studies. This is particularly relevant in the case of many diseases of the human central nervous system that have no suitable animal model, such as Alzheimer's disease, Huntington's chorea, and schizophrenia.In response to the need for brain tissues for scientific investigation, the U.S. Public Health Service has . . .Keywords
This publication has 9 references indexed in Scilit:
- Animals in ResearchPublished by American Medical Association (AMA) ,1988
- Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides.Proceedings of the National Academy of Sciences, 1987
- Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's DiseaseScience, 1987
- Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer LocusScience, 1987
- The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptorNature, 1987
- The Autopsy as a Measure of Accuracy of the Death CertificateNew England Journal of Medicine, 1985
- Book ReviewEsophageal Function in Health and DiseaseNew England Journal of Medicine, 1984
- The Value of the Autopsy in Three Medical ErasNew England Journal of Medicine, 1983
- The Autopsy: Its Decline and a Suggestion for Its RevivalNew England Journal of Medicine, 1978