Development and characterization of monoclonal antibodies to Marek's disease tumor-associated surface antigen
Open Access
- 1 August 1983
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 41 (2) , 851-854
- https://doi.org/10.1128/iai.41.2.851-854.1983
Abstract
Four monoclonal antibodies, A35, B94, EB29, and G152, against Marek's disease tumor-associated surface antigen have been developed and their specificities studied against a panel of Marek's disease and lymphoid leukosis primary tumors; Marek's disease, and lymphoid leukosis, and reticuloendotheliosis lymphoblastoid cell lines; and normal chicken cells. A35 and G152 are of the immunoglobulin M class, and B94 and EB29 are of the immunoglobulin G1 subclass.Keywords
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