Congenital Cystic Adenomatoid Malformation of the Lung Associated With Abdominal Musculature Deficiency (Prune Belly)

Abstract
"Prune belly"—a deficiency of abdominal niusculature usually associated with urinary tract anomalies and cryptorchidism—has been explained by numerous theories. Some postulate a primary defect of abdominal musculature, producing renal dysfunction1; others suggest the reverse2; other proposals include a sex-linked inherited trait3, and an intrauterine insult (between six and ten weeks of gestation).4 Congenital cystic adenomatoid malformation of the lung (CCAM) is a distinct morphological entity, characterized by a proliferation of cysts lined by bronchiolar-like epithelium and a lack of cartilage and seromucous glands.5 CCAM has been postulated to be a harnartoma,6 a focal type of pulmonary dysplasia,7 or a development anomaly.8