Cord Blood Reverse T3in Congenital Hypothyroidism*
- 1 February 1978
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 46 (2) , 336-338
- https://doi.org/10.1210/jcem-46-2-336
Abstract
Reverse triiodothyronine (rT3) was measured in cord serum from 5 infants with congenital hypothyroidism and compared with normal values in 70 euthyroid control infants. The mean (and SEM) value in the affected infants (135 ± 12 ng/dl) wassignificantly lower than that in the control population (270 ± 9 ng/dl). However, the large overlap in range of concentrations in affected and control infants indicates that newborn screening based on the determination of rT3 in cord blood specimens offers no advantage qver present screening methods. (J Clin Endocrinol Metab46: 336, 1978)This publication has 4 references indexed in Scilit:
- Serum T4, TBG, T3Uptake, T3, Reverse T3and TSH Concentrations in Children 1 to 15 Years of AgeJournal of Clinical Endocrinology & Metabolism, 1977
- Measurements of 3,3′5′-Triiodothyronine (Reverse T3), 3,3′-L-Diiodothyronine, T3, and T4 in Human Amniotic Fluid and in Cord and Maternal Serum1 2Journal of Clinical Endocrinology & Metabolism, 1976
- Neonatal thyroid function in congenital hypothyroidismThe Journal of Pediatrics, 1976
- EVALUATION OF THREE THYROID-FUNCTION SCREENING TESTS FOR DETECTING NEONATAL HYPOTHYROIDISMThe Lancet, 1976