• 1 January 1985
    • journal article
    • research article
    • Vol. 21  (5) , 418-420
Abstract
Danzaol, an impeded androgen, was used for treating 3 patients with chronic idiopathic thrombocytopenic purpura (ITP) refractory to corticosteroid therapy. Sustained remission was achieved in 1 of the 3 cases. A temporary response was obtained in the 2nd patient. In the last case, platelet count improved, but the patient died of severe interstitial pneumonitis. These observations confirm recent reports on the efficacy of danazol in the management of ITP and indicate the danazol treatment improves platelet counts in the majority of patients with refractory ITP, and in some cases may obviate the need for splenectomy.