Hemmung des γ-Aminobuttersäureabbaus durch Valerensäurederivate
- 1 December 1982
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 46 (12) , 219-220
- https://doi.org/10.1055/s-2007-971218
Abstract
The enzym system 2-oxoglutarataminotransferase/semisuccinaldehydoxireductase (E. C. 2.6.1.19/E.C. 1.2.1.16, Gabase) catalyzing the catabolism of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) is inhibited by mmol/l concentrations of valerenolic acid (20%) and acetylvalerenolic acid (38%). 1 mmol/l L-glutamic acid inhibited 59%, 0.1 mmol/l chlorogenic acid 69%.Keywords
This publication has 0 references indexed in Scilit: