Stratified Estimates of Influenza Vaccine Effectiveness by Prior Vaccination: Caution Required

Open Access

25 April 2013

journal article
research article
Published by Oxford University Press (OUP) in Clinical Infectious Diseases

Vol. 57 (3) , 474-476
https://doi.org/10.1093/cid/cit255

Abstract

To the Editor—Ohmit and colleagues recently reported intriguing results from the Household Influenza Vaccine Effectiveness (HIVE) study [1]. An unexpected finding of this study was that the vaccine effectiveness (VE) estimate suggested no protection with repeated vaccination (VE, −45%; 95% confidence interval [CI], −226 to 35), whereas for participants not vaccinated in the prior season, the vaccine was protective (VE, 62%; 95% CI, 17–82).

Keywords

INFLUENZA VACCINE
CONFIDENCE
VACCINE EFFECTIVENESS
HIVE
COLLEAGUES
VACCINATED IN THE PRIOR
OHMIT

This publication has 1 reference indexed in Scilit:

Influenza Vaccine Effectiveness in the Community and the Household
Clinical Infectious Diseases, 2013