Lovastatin in X-Linked Adrenoleukodystrophy
- 21 January 2010
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 362 (3) , 276-277
- https://doi.org/10.1056/nejmc0907735
Abstract
As reported previously in the Journal, lovastatin lowers levels of very-long-chain fatty acids in plasma in patients with X-linked adrenoleukodystrophy (X-ALD).1 Further studies did not reproduce this finding with the use of simvastatin in patients or with the use of lovastatin in X-ALD–knockout mice.2,3 Still, many patients with X-ALD worldwide receive lovastatin.Keywords
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