Evaluation of Human Diaphragm Contractility Using Mouth Pressure Twitches
- 1 May 1992
- journal article
- Published by American Thoracic Society in American Review of Respiratory Disease
- Vol. 145 (5) , 1064-1069
- https://doi.org/10.1164/ajrccm/145.5.1064
Abstract
Mouth (PmT), esophageal (PesT), and transdiaphragmatic pressure twitches (PdiT) in response to single supramaximal bilateral phrenic nerve shocks were recorded during relaxation between total lung capacity (TLC) and functional residual capacity (FRC) in five normal volunteers. The PmT versus PesT or PmT versus PdiT relationships, which were linearly correlated (all r greater than 0.76), were not affected by diaphragm fatigue and were reproducible on repeated determinations over a period exceeding 1 yr. The PmT versus lung volume relationship was also linear (all r greater than 0.72) and reproducible, and its changes following diaphragm fatigue reliably reflected the changes in diaphragm contractility. We conclude that PmT is a reliable measure of diaphragm pressure-generating capacity in normal individuals and has the potential of providing similar information in patients.Keywords
This publication has 4 references indexed in Scilit:
- Respiratory Muscle Fatigue: Report of the Respiratory Muscle Fatigue Workshop GroupAmerican Review of Respiratory Disease, 1990
- Twitch pressures in the assessment of diaphragm weakness.Thorax, 1989
- Effect of lung volume on in vivo contraction characteristics of human diaphragmJournal of Applied Physiology, 1987
- Abdominal and thoracic pressures at different lung volumesJournal of Applied Physiology, 1960