A Model for the Stereoselectivity of Radical Mediated Reductive Alkylation of Acyclic Enamines
- 1 January 1992
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1992 (03) , 211-213
- https://doi.org/10.1055/s-1992-21316
Abstract
The radical mediated reductive alkylation of enamines [e.g., (E)-1-phenyl-1-pyrrolidino-1-propene (1)] derived from propiophenone is investigated. The observed stereoselectivities are explained with a model based on semiempirical calculations of the radical intermediate conformation.Keywords
This publication has 0 references indexed in Scilit: