A Filamentous Distribution for the Herpes Simplex Virus Type 2-encoded Major DNA-binding Protein
- 1 July 1986
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 67 (7) , 1315-1325
- https://doi.org/10.1099/0022-1317-67-7-1315
Abstract
Monoclonal antibodies reacting with the herpes simplex virus (HSV)-encoded major DNA-binding protein defined an intracellular filamentous network. This network was associated predominantly with the infected cell nucleus and occurred in cells infected with HSV type 2. It did not co-distribute with microfilaments, microtubules or intermediate filaments, and DNA synthesis was required for its formation. We suggest explanations for the occurrence and function of this novel filamentous network structure.This publication has 27 references indexed in Scilit:
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