Methodologic European External Quality Assurance for DNA Sequencing: The EQUALseq Program

Open Access

1 April 2006

journal article
research article
Published by Oxford University Press (OUP) in Clinical Chemistry

Vol. 52 (4) , 716-727
https://doi.org/10.1373/clinchem.2005.061572

Abstract

Background: DNA sequencing is a key technique in molecular diagnostics, but to date no comprehensive methodologic external quality assessment (EQA) programs have been instituted. Between 2003 and 2005, the European Union funded, as specific support actions, the EQUAL initiative to develop methodologic EQA schemes for genotyping (EQUALqual), quantitative PCR (EQUALquant), and sequencing (EQUALseq). Here we report on the results of the EQUALseq program.

Keywords

This publication has 23 references indexed in Scilit:

Genetic variation analyses by Pyrosequencing
Published by Elsevier ,2005
Elevated factor VII as a risk factor for recurrent fetal loss
Thrombosis and Haemostasis, 2005
Prenatal Exclusion of Severe Factor VII Deficiency
Journal of Pediatric Hematology/Oncology, 2003
Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis
Gut, 2002
A review of DNA sequencing techniques
Quarterly Reviews of Biophysics, 2002
New DNA Sequencing Methods
Annual Review of Biomedical Engineering, 2001
Analysis of the genotypes and phenotypes of 37 unrelated patients with inherited factor VII deficiency
European Journal of Human Genetics, 2001
A new polymorphism for the RI22H mutation in hereditary pancreatitis
Gut, 2001
Gene Mutations in Children with Chronic Pancreatitis
Pancreatology, 2001
DNA sequencing with chain-terminating inhibitors
Proceedings of the National Academy of Sciences, 1977