Clarithromycin Resistance and Eradication of Helicobacter pylori in Children
- 1 July 2001
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 45 (7) , 2134-5
- https://doi.org/10.1128/aac.45.7.2134-2135.2001
Abstract
Outcome of Helicobacter pylori infection was analyzed in 61 children treated with a triple therapy including clarithromycin. Bacterial eradication was obtained in all children with clarithromycin-susceptible strains but not in children with clarithromycin-resistant ones ( P = 0.0001). H. pylori antimicrobial susceptibility is mandatory before choosing a treatment, and clarithromycin should be avoided in case of resistance.Keywords
This publication has 15 references indexed in Scilit:
- High Levels of Resistance to Metronidazole and Clarithromycin in Helicobacter pylori Strains in ChildrenJournal of Clinical Microbiology, 2001
- Role of antimicrobial susceptibility testing on efficacy of triple therapy in Helicobacter pylori eradicationAlimentary Pharmacology & Therapeutics, 2000
- Clarithromycin resistance in Helicobacter pylori infection: Does it matter?Journal of Gastroenterology and Hepatology, 2000
- Helicobacter pylori Infection in Children: A Consensus StatementJournal of Pediatric Gastroenterology and Nutrition, 2000
- Different Penicillin‐Binding Protein Profiles in Amoxicillin‐Resistant Helicobacter pyloriHelicobacter, 1999
- Treatment after failure: the problem of "non-responders"Gut, 1999
- Relationship between Helicobacter pylori eradication and reduced duodenal and gastric ulcer recurrence: A reviewGastroenterology, 1996
- Helicobacter pylori in Peptic Ulcer DiseaseJAMA, 1994
- Experience with‘triple’ anti‐Helicobacter pylori eradication therapy: side effects and the importance of testing the pre‐treatment bacterial isolate for metronidazole resistanceAlimentary Pharmacology & Therapeutics, 1992