Cyclic AMP and Platelet Function

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Abstract
MOST of the present understanding of the functions of blood platelets has developed in the past decade, although platelets were first described a century ago. Attention to their role in the body's economy was revived in 1961, when it was demonstrated1 that platelet aggregation could be produced by adenosine diphosphate (ADP), a compound present in all living cells. The subsequent 10 years have clarified many of the functions of platelets, which can be considered in three broad categories: they participate in the arrest of hemorrhage as building blocks in the formation of a hemostatic plug and as accelerators of the . . .