Effects of the Androgen Analog Mibolerone on Clinical and Subclinical Infectious Bursal Disease
- 1 January 1980
- journal article
- research article
- Published by JSTOR
- Vol. 24 (1) , 247-256
- https://doi.org/10.2307/1589784
Abstract
Mibolerone treatment (1.5 .mu.g/g feed) did not diminish the immunosuppressive effects of an early exposure (1 day old) to infectious bursal disease virus (IBDV) as indicated by Newcastle disease virus (NDV) hemagglutination-inhibition serological responses and resistance to NDV challenge following vaccination with an inactivated NDV vaccine at 14 days old. Treating Single-Comb White Leghorn chickens free of IBDV-specific maternal antibody with mibolerone (1.5 .mu.g/g of feed for the first 4 wk of life) decreased clinical and serological responses to IBDV infection at 4 wk old. This was evidenced by lower levels of IBDV-neutralizing and precipitating antibody and an increased resistance to clinical IBD.This publication has 0 references indexed in Scilit: