Clindamycin and diarrhea

Abstract
Of 298 outpatients receiving clindamycin for a variety of indications, diarrhea developed in 10 (3.4%); none were diagnosed as having pseudomembranous colitis. This is well within the range of relative frequencies of diarrhea development (0-22.2%) reported in 45 previous studies. Reliance solely on computer recorded instances of diarrhea yielded a substantial underestimate of diarrhea occurrence, but the rate was still significantly higher (P < .05) in clindamycin users than in nonusers.

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