SPONTANEOUS PERSISTENT ESTRUS IN A STRAIN OF ALBINO RATS

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Abstract
A strain of rats developed a strong tendency toward persistent ovarian follicles and accompanying vaginal cornification. This condition appears early in life in a high proportion of the population, becoming increasingly prevalent as the animals become older. In the same population, there is also a pronounced tendency toward delayed and difficult parturition. The continuous supply of estrin in animals which remain in estrus for long periods is at a sufficiently high level to produce changes in the uterus and tubes, simulating those which result from the continuous adm. of large amts. of estrogenic substances.

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