Unraveling Immune Privilege

Abstract
J. W. Streilein discusses the concept of immune privilege, which protects from rejection tissues grafted to certain sites in the body. The differences between immune-privileged sites and immune-privileged tissues are illustrated by two recent papers implicating the cell surface protein FasL in immune privilege in the eye ( Science , p. 1189 of this issue) and in the testis [D. Bellgrau et al ., Nature 377 , 630 (1995)].