Inherited Differences in Blood Group A Subtypes in Caucasians and Negroes
- 1 January 1971
- journal article
- Published by S. Karger AG in Human Heredity
- Vol. 21 (1) , 88-96
- https://doi.org/10.1159/000152389
Abstract
The blood group A subtypes of a Caucasian and a Negro population of Virginia were investigated, utilizing a standardized immunohemolytic system and lectins for quantitation of antigenic reactivity. The frequencies of subtypes and antigenic reactivities differed significantly between the two populations; the most striking differences were the high frequency of Ai (intermediate) in Negroes and high Ulex reactivities in all A subtypes and group·samples of Negroes. Family studies disclosed Ai to be inherited by one or more alleles. The Ai allele is fully dominant over A2 and is strongly suppressed in AiB individuals as A is suppressed in AjB and AB individuals.Keywords
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