Crystallization of a common cold virus, human rhinovirus 14: “Isomorphism” with poliovirus crystals

Abstract
Crystals of rhinovirus 14 were grown reproducibly. They diffract X-rays to a resolution of at least 3.5 .ANG.. The orthorhombic crystal unit cell contains 2 virions, each situated on a crystallographic 2-fold axis. At < 30-.ANG. resolution, the space group approximates to I222 with the particles possessing 222 pseudo crystallographic symmetry. The crystals are isomorphous with type I polio crystals suggesting, some similarities of structure between enteroviruses and rhinoviruses.