Adverse reactions in connection with zimeldine treatment — a review
- 1 August 1983
- journal article
- clinical trial
- Published by Wiley in Acta Psychiatrica Scandinavica
- Vol. 68 (s308) , 115-119
- https://doi.org/10.1111/j.1600-0447.1983.tb11110.x
Abstract
The results of clinical trials have shown that the general level of side-effects is substantially lower with zimeldine than with tricyclic antidepressants. Data from ordinary clinical usage in Sweden and the U.K. (as opposed to clinical research experience) shows a similar picture. Hypersensitivity reactions, characterized by fever, myalgia and/or arthralgia, and transient increases in transaminases, occur in approximately 1.5% of patients. In rare cases potentially serious neuropathies have been reported.Keywords
This publication has 2 references indexed in Scilit:
- The efficacy of zimeldine in preventing depressive episodes in recurrent major depressive disorders — a double‐blind placebo‐controlled studyActa Psychiatrica Scandinavica, 1983
- The safety of zimeldine in long‐term use in depressive illnessActa Psychiatrica Scandinavica, 1983