Electrical stimulation of osteogenesis in delayed union of the rabbit fibula
- 1 June 1983
- journal article
- research article
- Published by Springer Nature in Archives of orthopaedic and trauma surgery
- Vol. 101 (4) , 247-250
- https://doi.org/10.1007/bf00379938
Abstract
The present paper describes an experimental model where union was delayed in an osteotomy gap of the rabbit fibula by means of a silicone rubber spacer during 48 days. After the silicone spacer had been removed, electrical transistor regulated direct current of 20 microampères delivered through stainless steel electrodes was used to stimulate osteogenesis on the right side during 62 days. On the left side a sham operation inserting stainless steel electrodes without current was performed. In one out of six animals overbridging callus was received on the stimulated side. In the rest of the animals a high frequency of synostoses between the fibular ends and the tibia was found. There was no significant difference in synostosis formation between the right and the left side. No adverse effect of the current could be detected histologically. Diese Arbeit beschreibt ein experimentelles Modell mit Kaninchen, wo die Heilung der Fibulaosteotomien wdhrend 48 Tagen mit Hilfe von Silikongummicylindern verzögert wurde. Nachdem die Gummicylinder extrahiert waren, wurde der Heilungsprozeß auf der rechten Seite mit konstantem, transistorregliertem Gleichstrom à 20 Mikro-Ampère stimuliert, welcher den Fibulaenden mit Stahldrahtelektroden zugeführt wurde. Auf der linken Seite, die zur Kontrolle diente, wurden stromlose Elektroden an den Fibulaenden angebracht. Nach 62 Tagen Stimulation wies ein Tier reichlich überbrückender Callus an der Osteotomistelle auf, während die übrigen Tiere in hohem Grade Synostosen zwischen den Fibulaenden and Tibia aufwiesen. Die Anzahl Synostosen war auf der stimulierten Seite größer. Die histologische Analyse zeigte keine Spuren von Neoplasie.Keywords
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