Management of Stress Gastritis
- 1 September 1991
- journal article
- Published by SAGE Publications in Journal of Intensive Care Medicine
- Vol. 6 (5) , 257-267
- https://doi.org/10.1177/088506669100600504
Abstract
Management of stress gastritis is primarily directed toward prevention of gastrointestinal bleeding. Antacids and H2 blockers have been the standard agents used for prophylactic therapy in critically ill patients. However, growing evidence that gastric alkalization leads to an increased incidence of nosocomial pneumonias has led to the development of other prophylactic agents that do not decrease gastric acidity. These cytoprotective agents presumably enhance gastric mucosal defenses and stimulate mucosal repair. Approximately 3% of patients bleed despite prophylactic therapy. Bleeding is usually controlled with intensive medical management, and the need for surgical intervention is rare.Keywords
This publication has 113 references indexed in Scilit:
- Nosocomial Pneumonia in Intubated Patients Given Sucralfate as Compared with Antacids or Histamine Type 2 BlockersNew England Journal of Medicine, 1987
- PREVENTION OF STRESS BLEEDING AND THE RISK OF NOSOCOMIAL PNEUMONIA IN VENTILATED ICU-PATIENTSAnesthesiology, 1987
- Overview of misoprostol clinical experienceDigestive Diseases and Sciences, 1986
- Direct and adaptive cytoprotectionDigestive Diseases and Sciences, 1986
- The gastric mucosal barrierDigestive Diseases and Sciences, 1985
- The pathophysiology of peptic ulcer diseaseDigestive Diseases and Sciences, 1985
- Inhibitory effect of intragastric glucose on gastric acid secretion and gastric emptying of liquids in manDigestive Diseases and Sciences, 1983
- Antacid versus Cimetidine in Preventing Acute Gastrointestinal BleedingNew England Journal of Medicine, 1980
- Antacid Titration in the Prevention of Acute Gastrointestinal BleedingNew England Journal of Medicine, 1978
- Divergent Nature of Gastric Mucosal Permeability and Gastric Acid Secretion in Sick Patients with General Surgical and Neurosurgical DiseaseAnnals of Surgery, 1973