Parental origin of chromosomal non‐disjunction in a 49,XXXXY male using recombinant‐DNA techniques

Abstract
We have analyzed the origin, in a patient with 49,XXXXY, of the four X‐chromosomes by means of recombinant DNA techniques. We found a maternal origin of the four X‐chromosomes due to non‐disjunctions in the first and second meiotic divisions.