The Nature, Distribution and Causes of Traumatic Brain Injury
- 1 October 1995
- journal article
- review article
- Published by Wiley in Brain Pathology
- Vol. 5 (4) , 397-406
- https://doi.org/10.1111/j.1750-3639.1995.tb00618.x
Abstract
The identification and interpretation of brain damage resulting from a non-missile head injury is often not easy with the result that the most obvious structural damage identified postmortem may not be the most important in trying to establish clinicopathological correlations. For example patients with a fracture of the skull, quite severe cerebral contusions or a large intracranial haematoma that is successfully treated can make an uneventful and complete recovery if no other types of brain damage are present. However, not infrequently more subtle forms of pathology are present and ones that can only be identified microscopically. A systematic and pragmatic approach through the autopsy is therefore required and one that recognises the need for tissue to be retained in ways that are appropriate for cellular and molecular studies.Keywords
This publication has 73 references indexed in Scilit:
- Axonal injury: a universal consequence of fatal closed head injury?Acta Neuropathologica, 1995
- β-Amyloid precursor protein (βAPP) as a marker for axonal injury after head injuryNeuroscience Letters, 1993
- Focal axonal injury: the early axonal response to stretchJournal of Neurocytology, 1991
- Diffuse axonal injury in head trauma.Journal of Neurology, Neurosurgery & Psychiatry, 1989
- Brain damage in fatal non-missile head injury without high intracranial pressure.Journal of Clinical Pathology, 1988
- Analysis of abnormalities in pituitary gland in non-missile head injury: study of 100 consecutive cases.Journal of Clinical Pathology, 1986
- Biomechanics of Acute Subdural HematomaPublished by Wolters Kluwer Health ,1982
- Survival after traumatic ponto-medullary tear.Journal of Neurology, Neurosurgery & Psychiatry, 1982
- PATIENTS WITH HEAD INJURY WHO TALK AND DIEThe Lancet, 1975
- Brain-stem lesions after head injury.Journal of Clinical Pathology, 1970