Age incidence curves for cancer.
- 1 April 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (4) , 1341-1342
- https://doi.org/10.1073/pnas.74.4.1341
Abstract
Age incidence curves for [human] carcinomas tend to be linear on doubly logarithmic graphs. This fact was used to support the somatic mutation hypothesis. This should also be expected on the epigenetic hypothesis when reversible cellular changes are programmed to occur randomly. Such changes could be programmed differently to obtain the age incidence curves observed for other cancers, e.g., leukemias and sarcomas.This publication has 4 references indexed in Scilit:
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