Intubating conditions using cisatracurium after induction of anaesthesia with thiopentone
Open Access
- 1 October 1997
- journal article
- clinical trial
- Published by Wiley in Anaesthesia
- Vol. 52 (10) , 998-1000
- https://doi.org/10.1111/j.1365-2044.1997.192-az0328.x
Abstract
We studied tracheal intubation conditions produced by the muscle relaxant, cisatracurium, following induction of anaesthesia with fentanyl (2 μgkg−1) and thiopentone (6 mgkg−1). Sixty patients were randomly assigned to receive cisatracurium in a single bolus dose of either 0.15 or 0.20 mgkg−1. Tracheal intubation was commenced 120 s after injection of the relaxant. The mean (SD) time taken to achieve intubation was significantly shorter in the 0.20 mgkg−1 group (137 (16) s) than the 0.15 mgkg−1 group (149 (12) s; p < 0.05). The intubating conditions were better after the larger dose. Our results suggest that when anaesthesia is induced using thiopentone, a dose of 0.20 mgkg−1 of cisatracurium is recommended to ensure satisfactory intubating conditions.Keywords
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