Endoplasmic reticulum stress exacerbates ischemia‐reperfusion‐induced apoptosis through attenuation of Akt protein synthesis in human choriocarcinoma cells
Open Access
- 13 December 2006
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 21 (3) , 872-884
- https://doi.org/10.1096/fj.06-6054com
Abstract
Oxidative stress is central to ischemia‐reperfusion injury. The role of the endoplasmic reticulum (ER) in this process is uncertain. In ER signaling, PERK‐Nrf2 and Ire‐CHOP are two pathways that dete...Keywords
Funding Information
- Wellcome Trust (069027/Z/02/Z)
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