Augmentin compared with amoxycillin in treating uncomplicated gonorrhoea.
- 1 June 1985
- journal article
- research article
- Published by BMJ in Sexually Transmitted Infections
- Vol. 61 (3) , 165-167
- https://doi.org/10.1136/sti.61.3.165
Abstract
Patients (138 men and 82 women) with uncomplicated gonorrhea who were entered into a randomized double blind trial were studied and treated with either Augmentin (amoxycillin 3 g and potassium clavulanate 125 mg) or amoxycillin 3 g, with probenecid 1 g by mouth in all cases. Seven (6.5%) of 108 patients treated with Augmentin were still culture positive after tratment, compared with 15 (13.4%) of 112 of those treated with amoxycliin. Penicillinase(.beta. lactamase) producing strians of Neisseria gonorrhoeae (PPNG) were found in 23 (10.5%) patients, of whom 10 were treated with Augmentin and 13 with amoxycillin. Treatment failed in al 13 patients who received amoxycillin. Augmentin was shown to be an effective treatment for gonorrhoea caused by PPNG strains.This publication has 5 references indexed in Scilit:
- Imported penicillinase producing Neisseria gonorrhoeae becomes endemic in London.Sexually Transmitted Infections, 1983
- Single dose oral amoxycillin and clavulanic acid in the treatment of gonococcal urethritis in males.1982
- Penicillinase-producing Neisseria gonorrhoeae in Great Britain, 1977-81: alarming increase in incidence and recent development of endemic transmission.BMJ, 1982
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- SPECTINOMYCIN-RESISTANT PENICILLINASE-PRODUCING NEISSERIA GONORRHOEAEThe Lancet, 1981