LOW RESERVE ALBUMIN FOR BINDING OF BILIRUBIN IN NEONATES WITH DEFICIENCY OF BILIRUBIN EXCRETION AND BRONZE BABY SYNDROME

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Abstract
The plasma reserve albumin concentration for binding of bilirubin was low in 4 newborn infants with deficiency of bilirubin excretion, of whom 2 had the bronze baby syndrome. The risk of bilirubin encephalopathy was increased. The ratio of binding fraction of albumin, i.e., unconjugated bilirubin plus reserve albumin, to total albumin was low. Possible causes of the low reserve albumin concentration and the ratio are discussed.