Regiospecific 1,4 addition of a propargylic anion. A general synthon for 2-substituted propargylamines as potential catalytic irreversible enzyme inhibitors.
- 31 December 1975
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 16 (38) , 3337-3340
- https://doi.org/10.1016/s0040-4039(00)91443-6
Abstract
No abstract availableKeywords
This publication has 8 references indexed in Scilit:
- Conjugate addition of 1 - trialkylsilylpropynylcopper derivatives; a new synthesis of 1, 5-allenic and acetylenic olefinsTetrahedron Letters, 1974
- γ-aminobutyric acid and nervous system function—A perspectiveBiochemical Pharmacology, 1974
- Chemistry and Enzymology of k cat InhibitorsScience, 1974
- Propargyl amine-induced irreversible inhibition of non-flavin-linked a mine oxidasesBiochemical Pharmacology, 1974
- Acetylenic enzyme inactivators. Inactivation of .gamma.-cystathionase, in vitro and in vivo by propargylglycineJournal of the American Chemical Society, 1973
- Position-specific alkylation of lithio-1-trimethylsilylpropyne, a useful new route to acetylenes and 1, 5-dienesTetrahedron Letters, 1968
- 1-Ethynylphenethylamine1Journal of Medicinal Chemistry, 1966
- The Preparation of Some Acetylenic Primary Amines1Journal of the American Chemical Society, 1953