The Chemical Nature of the Subcutaneous Fat in the Normal and Sclerematous Infant

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Abstract
The iodine number of the normal subcutaneous fat is lowest at birth, increases to the adult value in the 8th-12th month, with a decrease in melting point with age. The saponification value is almost constant (200). In similar fat from 4 cases of sclerema neonatorum, higher melting points and lower iodine numbers were obtained. This is considered due to an excess of glycerides of higher fatty acids (probably palmitic), which results in a slight decrease in the oleic acid content of the fat. Subcutaneous tissue in sclerema neonatorum shows a definite increase in its content of Ca, P, and cholesterol.

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