Clonidine (Haemiton®) as a Reliable Stimulus of Growth Hormone Secretion in Patients with Short Stature
- 1 May 1983
- journal article
- research article
- Published by Georg Thieme Verlag KG in Experimental and Clinical Endocrinology & Diabetes
- Vol. 81 (03) , 315-320
- https://doi.org/10.1055/s-0029-1210242
Abstract
In 14 patients with short stature aged 4–14 years the effect of clonidine has been investigated. A single oral dose of 0.15 mg/m2 surface area is followed by a marked increase of hGH concentration in blood with a peak value between 60 and 90 min after the administration of the drug. The hGH increase caused by clonidine was comparable to the rise during insulin-induced hypoglycemia. In 5 patients both stimuli failed to increase hGH release. The test procedure is simple. It shows only minimum side effects and can therefore be especially recommended in outpatients.Keywords
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