STUDY OF PECULIAR PROPERTIES OF FUSIDIN BIOSYNTHESIS BY FUSIDIUM-COCCINEUM, STRAIN-257A

  • 1 January 1977
    • journal article
    • research article
    • Vol. 22  (1) , 29-32
Abstract
The physiology F. coccineum strain 257 A, an organism producing fusidin, was studied. Increased concentrations of Ca sources in the medium stimulated production of fusidin. High concentrations of amino acid-peptide form of N of corn-steep liquor decreased production, while the protein form of N of soybean meal increased the antibiotic production. The low rate of fusidin biosynthesis on the medium with higher contents of the corn-steep liquor N was probably associated with the consumption of the significant part of C in the medium for formation of mycelium. The concentration of the easily utilizable forms of N is probably a regulator of the growth process of F. coccineum 257 A and fusidin production.

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