Gentamicin in Pediatrics. II. Treatment of Severe Urinary-Tract Infections Caused by Gram-Negative Bacilli and of Staphylococcal Infections

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Abstract
More than 100 cases of severe gram-negative infection of the urinary tract in children were treated for five to 10 days with gentamicin at a dosage of 2 mg/kg per day; more than 80% of the patients responded favorably, and no adverse reactions were noted. The activity of gentamicin against coagulase-positive and coagulase-negative staphylococci is reported, and the use of the drug in the control and elimination of colonization of ventriculoatrial shunts by coagulase-negative staphylococci is discussed.