NEUROLEPTANAESTHESIA FOR MAJOR SURGERY: Experience with 500 Cases

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Abstract
Experience of neuroleptanaesthesia using droperidol and fentanyl or phenoperidine for 500 patients undergoing elective major surgery is reported. In the majority of patients the technique offers considerable advantages such as smooth, uncomplicated induction, cardiovascular stability during maintenance of anaesthesia and a recovery phase notable for rapid return of consciousness and the absence of restlessness and vomiting. Arterial pressure decreases during induction of anaesthesia tended to be greater in the elderly patients, but were always rapidly restored by infusion of Hartmann's solution, and vasopressors were never needed. Rigidity immediately following induction occured in a small percentage of patients. It is concluded that this technique has advantages which make it particularly suitable for major surgery even in elderly and poor-risk patients.

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