Is the finding of the PROFESS study consistent with predictions of network meta-analysis?
Open Access
- 13 May 2008
- journal article
- research article
- Published by Oxford University Press (OUP) in European Heart Journal
- Vol. 29 (20) , 2580
- https://doi.org/10.1093/eurheartj/ehn397
Abstract
The network meta-analysis performed by Thijs et al.1 found that the use of the combination of aspirin and dipyridamole (ASA + D) is better than thienopyridines or aspirin alone in secondary prevention of vascular events after transient ischaemic attack or stroke. The accompanying editorial2 suggested that the PROFESS study could be used to assess the validity of these findings. The PROFESS study results are now available3 and suggest that ASA + D has a similar efficacy to clopidegrel, which was not predicted by the meta-analysis.Keywords
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