Antifungal agents. 4. Chemical modification of antibiotics from Polyangium cellulosum var fulvum. Ester and amide analogues of ambruticin
- 1 September 1979
- journal article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 22 (9) , 1144-1147
- https://doi.org/10.1021/jm00195a031
Abstract
A series of ester and amide analogues of ambruticin (1) was prepared. The analogues were tested against Histoplasma capsulatum, Microsporum fulvum, Candida albicans and Streptococcus pyogenes. Structure-activity relationships are described.Keywords
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