Physical fitness and risk of myocardial infarction in Copenhagen males aged 40-59: a five- and seven-year follow-up study.

Abstract
A follow-up study on 5249 Copenhagen males showed that incidence of myocardial infarction was related to level of physical fitness at time of entry into the study, as determined by indirect measurement of maximal O2 uptake. Men having a physical fitness level within lowest 5th of total sample had a 3-fold higher incidence of myocardial infarction than men in upper 2/5. This increased risk was independent of smoking habits and serum cholesterol level but was partly or entirely dependent on blood pressure levels, as shown by use of multiple logistic regression analysis. Men with heaviest occupational physical activity had a higher risk of myocardial infarction than men with sedentary jobs. Data on leisure-time physical activity and risk of coronary heart disease indicated that only physical activity inducing a physical training effect was related to decreased risk.

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